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Relationship between crown-like structures and sex-steroid hormones in breast adipose tissue and serum among postmenopausal breast cancer patients

BACKGROUND: Postmenopausal obesity is associated with increased circulating levels of androgens and estrogens and elevated breast cancer risk. Crown-like structures (CLS; microscopic foci of dying adipocytes surrounded by macrophages) are proposed to represent sites of increased aromatization of and...

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Pubblicato in:Breast Cancer Res
Autori principali: Mullooly, Maeve, Yang, Hannah P., Falk, Roni T., Nyante, Sarah J., Cora, Renata, Pfeiffer, Ruth M., Radisky, Derek C., Visscher, Daniel W., Hartmann, Lynn C., Carter, Jodi M., Degnim, Amy C., Stanczyk, Frank Z., Figueroa, Jonine D., Garcia-Closas, Montserrat, Lissowska, Jolanta, Troester, Melissa A., Hewitt, Stephen M., Brinton, Louise A., Sherman, Mark E., Gierach, Gretchen L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244534/
https://ncbi.nlm.nih.gov/pubmed/28103902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0791-4
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