Relationship between crown-like structures and sex-steroid hormones in breast adipose tissue and serum among postmenopausal breast cancer patients

BACKGROUND: Postmenopausal obesity is associated with increased circulating levels of androgens and estrogens and elevated breast cancer risk. Crown-like structures (CLS; microscopic foci of dying adipocytes surrounded by macrophages) are proposed to represent sites of increased aromatization of and...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Mullooly, Maeve, Yang, Hannah P., Falk, Roni T., Nyante, Sarah J., Cora, Renata, Pfeiffer, Ruth M., Radisky, Derek C., Visscher, Daniel W., Hartmann, Lynn C., Carter, Jodi M., Degnim, Amy C., Stanczyk, Frank Z., Figueroa, Jonine D., Garcia-Closas, Montserrat, Lissowska, Jolanta, Troester, Melissa A., Hewitt, Stephen M., Brinton, Louise A., Sherman, Mark E., Gierach, Gretchen L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244534/
https://ncbi.nlm.nih.gov/pubmed/28103902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0791-4
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