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Size-selective separation and overall-amplification of cell-free fetal DNA fragments using PCR-based enrichment

This study aimed to establish a method for the selective amplification of cell-free fetal DNA (cffDNA) in maternal plasma and preserve the integrity of DNA fragments during amplification, thereby providing a sufficient amount of cffDNA to meet the requirement of routine non-invasive prenatal testing...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Yang, Qiwei, Du, Zhenwu, Song, Yang, Gao, Sujie, Yu, Shan, Zhu, He, Ren, Ming, Zhang, Guizhen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244409/
https://ncbi.nlm.nih.gov/pubmed/28102322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40936
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