Activation of COX-2/PGE(2) Promotes Sapovirus Replication via the Inhibition of Nitric Oxide Production

Enteric caliciviruses in the genera Norovirus and Sapovirus are important pathogens that cause severe acute gastroenteritis in both humans and animals. Cyclooxygenases (COXs) and their final product, prostaglandin E(2) (PGE(2)), are known to play important roles in the modulation of both the host re...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Alfajaro, Mia Madel, Choi, Jong-Soon, Kim, Deok-Song, Seo, Ja-Young, Kim, Ji-Yun, Park, Jun-Gyu, Soliman, Mahmoud, Baek, Yeong-Bin, Cho, Eun-Hyo, Kwon, Joseph, Kwon, Hyung-Jun, Park, Su-Jin, Lee, Woo Song, Kang, Mun-Il, Hosmillo, Myra, Goodfellow, Ian, Cho, Kyoung-Oh
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Virus-Cell Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244346/
https://ncbi.nlm.nih.gov/pubmed/27881647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01656-16
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