Phosphatidylinositol 3-Kinase/Akt and MEK/ERK Signaling Pathways Facilitate Sapovirus Trafficking and Late Endosomal Acidification for Viral Uncoating in LLC-PK Cells

Sapovirus, an important cause of acute gastroenteritis in humans and animals, travels from the early to the late endosomes and requires late endosomal acidification for viral uncoating. However, the signaling pathways responsible for these viral entry processes remain unknown. Here we demonstrate th...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Soliman, Mahmoud, Kim, Deok-Song, Park, Jun-Gyu, Kim, Ji-Yun, Alfajaro, Mia Madel, Baek, Yeong-Bin, Cho, Eun-Hyo, Park, Chul-Ho, Kang, Mun-Il, Park, Sang-Ik, Cho, Kyoung-Oh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258943/
https://ncbi.nlm.nih.gov/pubmed/30282712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01674-18
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