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Development of an Improved System for the Generation of Knockout Mutants of Amycolatopsis sp. Strain ATCC 39116

The Gram-positive actinomycete Amycolatopsis sp. strain ATCC 39116 is used for the industrial production of natural vanillin. Previously, the only gene deletion performed in this strain targeted the gene vdh, coding for a vanillin dehydrogenase. The generation of this mutant suffered from a high num...

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Publicado en:Appl Environ Microbiol
Autores principales: Meyer, Florian, Pupkes, Hilke, Steinbüchel, Alexander
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244302/
https://ncbi.nlm.nih.gov/pubmed/27913417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02660-16
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