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The Rb tumor suppressor is required for stress erythropoiesis

The retinoblastoma tumor suppressor gene plays important roles in cell cycle control, differentiation and survival during development and is functionally inactivated in most human cancers. Early studies using gene targeting in mice suggested a critical role for pRb in erythropoiesis, while more rece...

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Detalhes bibliográficos
Main Authors: Spike, Benjamin T, Dirlam, Alexandra, Dibling, Benjamin C, Marvin, James, Williams, Bart O, Jacks, Tyler, Macleod, Kay F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC524396/
https://ncbi.nlm.nih.gov/pubmed/15457215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600432
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