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Hypoxic stress underlies defects in erythroblast islands in the Rb-null mouse

Definitive erythropoiesis occurs in islands composed of a central macrophage in contact with differentiating erythroblasts. Erythroid maturation including enucleation can also occur in the absence of macrophages both in vivo and in vitro. We reported previously that loss of Rb induces cell-autonomou...

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Detalles Bibliográficos
Main Authors: Spike, Benjamin T., Dibling, Benjamin C., Macleod, Kay F.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976369/
https://ncbi.nlm.nih.gov/pubmed/17557897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-01-069104
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