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NSCL-1 and NSCL-2 synergistically determine the fate of GnRH-1 neurons and control necdin gene expression
To study the role of the bHLH genes NSCL-1 and NSCL-2 in the development of GnRH-1 neurons, we have generated compound mutant mice. Mutant animals die at birth and show a virtually complete absence of GnRH-1 neurons in the posterior parts of the brain at E18.5 and an aberrant morphology of the remai...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524395/ https://ncbi.nlm.nih.gov/pubmed/15470499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600431 |
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