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PNKP Mutations Identified by Whole-Exome Sequencing in a Norwegian Patient with Sporadic Ataxia and Edema

We identified PNKP mutations in a Norwegian woman with AOA. This patient had the typical findings with cognitive dysfunction, peripheral neuropathy, cerebellar dysarthria, horizontal nystagmus, oculomotor apraxia, and severe truncal and appendicular ataxia. In addition, she had hypoalbuminemia and m...

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Publicat a:Cerebellum
Autors principals: Tzoulis, C., Sztromwasser, Paweł, Johansson, Stefan, Gjerde, Ivar Otto, Knappskog, Per, Bindoff, L. A.
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243888/
https://ncbi.nlm.nih.gov/pubmed/27165045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12311-016-0784-y
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