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Structure of the MutL C-terminal domain: a model of intact MutL and its roles in mismatch repair

MutL assists the mismatch recognition protein MutS to initiate and coordinate mismatch repair in species ranging from bacteria to humans. The MutL N-terminal ATPase domain is highly conserved, but the C-terminal region shares little sequence similarity among MutL homologs. We report here the crystal...

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Bibliografiska uppgifter
Huvudupphovsmän: Guarné, Alba, Ramon-Maiques, Santiago, Wolff, Erika M, Ghirlando, Rodolfo, Hu, Xiaojian, Miller, Jeffrey H, Yang, Wei
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2004
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC524388/
https://ncbi.nlm.nih.gov/pubmed/15470502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600412
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