Structure of the MutL C-terminal domain: a model of intact MutL and its roles in mismatch repair

MutL assists the mismatch recognition protein MutS to initiate and coordinate mismatch repair in species ranging from bacteria to humans. The MutL N-terminal ATPase domain is highly conserved, but the C-terminal region shares little sequence similarity among MutL homologs. We report here the crystal...

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Publié dans:	EMBO J
Auteurs principaux:	Guarné, Alba, Ramon-Maiques, Santiago, Wolff, Erika M, Ghirlando, Rodolfo, Hu, Xiaojian, Miller, Jeffrey H, Yang, Wei
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2004
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC524388/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15470502/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600412
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