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Phospholipase C-ε signaling mediates endothelial cell inflammation and barrier disruption in acute lung injury

Phospholipase C-ε (PLC-ε) is a unique PLC isoform that can be regulated by multiple signaling inputs from both Ras family GTPases and heterotrimeric G proteins and has primary sites of expression in the heart and lung. Whereas the role of PLC-ε in cardiac function and pathology has been documented,...

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Bibliografiska uppgifter
I publikationen:Am J Physiol Lung Cell Mol Physiol
Huvudupphovsmän: Bijli, Kaiser M., Fazal, Fabeha, Slavin, Spencer A., Leonard, Antony, Grose, Valerie, Alexander, William B., Smrcka, Alan V., Rahman, Arshad
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243226/
https://ncbi.nlm.nih.gov/pubmed/27371732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00069.2016
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