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Phospholipase C-ε signaling mediates endothelial cell inflammation and barrier disruption in acute lung injury
Phospholipase C-ε (PLC-ε) is a unique PLC isoform that can be regulated by multiple signaling inputs from both Ras family GTPases and heterotrimeric G proteins and has primary sites of expression in the heart and lung. Whereas the role of PLC-ε in cardiac function and pathology has been documented,...
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| Publicado no: | Am J Physiol Lung Cell Mol Physiol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5243226/ https://ncbi.nlm.nih.gov/pubmed/27371732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00069.2016 |
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