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The lipid phosphatase myotubularin is essential for skeletal muscle maintenance but not for myogenesis in mice
Myotubularin is a ubiquitously expressed phosphatase that acts on phosphatidylinositol 3-monophosphate [PI(3)P], a lipid implicated in intracellular vesicle trafficking and autophagy. It is encoded by the MTM1 gene, which is mutated in X-linked myotubular myopathy (XLMTM), a muscular disorder charac...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2002
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC524320/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12391329/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.212498399 |
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