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Transcriptional Selectivity of Epigenetic Therapy in Cancer

A central challenge in the development of epigenetic cancer therapy is the ability to direct selectivity in modulating gene expression for disease-selective efficacy. To address this issue, we characterized by RNA-seq, DNA methylation and ChIP-seq analyses the epigenetic response of a set of colon,...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Sato, Takahiro, Cesaroni, Matteo, Chung, Woonbok, Panjarian, Shoghag, Tran, Anthony, Madzo, Jozef, Okamoto, Yasuyuki, Zhang, Hanghang, Chen, Xiaowei, Jelinek, Jaroslav, Issa, Jean-Pierre J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243171/
https://ncbi.nlm.nih.gov/pubmed/27879268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0834
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