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Structure of Penta-Alanine Investigated by Two-Dimensional Infrared Spectroscopy and Molecular Dynamics Simulation

We have studied the structure of (Ala)(5), a model unfolded peptide, using a combination of 2D IR spectroscopy and molecular dynamics (MD) simulation. Two different isotopomers, each bis-labeled with (13)C=O and (13)C=(18)O, were strategically designed to shift individual site frequencies and uncoup...

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Bibliographic Details
Published in:J Phys Chem B
Main Authors: Feng, Yuan, Huang, Jing, Kim, Seongheun, Shim, Ji Hyun, MacKerell, Alexander D., Ge, Nien-Hui
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243129/
https://ncbi.nlm.nih.gov/pubmed/27299801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.6b02608
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