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Simulation of two-dimensional infrared spectroscopy of amyloid fibrils

We propose to use infrared coherent two-dimensional correlation spectroscopy (2DCS) to characterize the fibril structure of Ab42, the dominant composition of Ab deposit, which is crucial for investigating its toxicity and aggregation mechanism. By optimizing the pulse polarization configurations wit...

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Detalhes bibliográficos
Main Authors: Zhuang, Wei, Abramavicius, Darius, Voronine, Dimitrii V., Mukamel, Shaul
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1964843/
https://ncbi.nlm.nih.gov/pubmed/17675411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700392104
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