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Simulation of two-dimensional infrared spectroscopy of amyloid fibrils

We propose to use infrared coherent two-dimensional correlation spectroscopy (2DCS) to characterize the fibril structure of Ab42, the dominant composition of Ab deposit, which is crucial for investigating its toxicity and aggregation mechanism. By optimizing the pulse polarization configurations wit...

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Bibliografische gegevens
Hoofdauteurs: Zhuang, Wei, Abramavicius, Darius, Voronine, Dimitrii V., Mukamel, Shaul
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1964843/
https://ncbi.nlm.nih.gov/pubmed/17675411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700392104
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