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Simulation of two-dimensional infrared spectroscopy of amyloid fibrils
We propose to use infrared coherent two-dimensional correlation spectroscopy (2DCS) to characterize the fibril structure of Ab42, the dominant composition of Ab deposit, which is crucial for investigating its toxicity and aggregation mechanism. By optimizing the pulse polarization configurations wit...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1964843/ https://ncbi.nlm.nih.gov/pubmed/17675411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700392104 |
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