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Simulation of two-dimensional infrared spectroscopy of amyloid fibrils

We propose to use infrared coherent two-dimensional correlation spectroscopy (2DCS) to characterize the fibril structure of Ab42, the dominant composition of Ab deposit, which is crucial for investigating its toxicity and aggregation mechanism. By optimizing the pulse polarization configurations wit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhuang, Wei, Abramavicius, Darius, Voronine, Dimitrii V., Mukamel, Shaul
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1964843/
https://ncbi.nlm.nih.gov/pubmed/17675411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700392104
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