PUMA and NF-kB Are Cell Signaling Predictors of Reovirus Oncolysis of Breast Cancer

BACKGROUND AND PURPOSE: Reovirus is a ubiquitous RNA virus that exploits aberrant signaling pathways for its replication. The oncolytic potential of reovirus against numerous cancers under pre-clinical/clinical conditions has been documented by us and others. Despite its proven clinical activity, th...

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Pubblicato in:PLoS One
Autori principali: Thirukkumaran, Chandini, Shi, Zhong-Qiao, Thirukkumaran, Ponnampalam, Luider, Joanne, Kopciuk, Karen, Spurrell, Jason, Elzinga, Kate, Morris, Don
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243128/
https://ncbi.nlm.nih.gov/pubmed/28099441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168233
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