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Assembly of combinatorial antibody libraries on phage surfaces: the gene III site.

A phagemid system was developed for the monovalent display of combinatorial antibody Fab libraries on the surface of filamentous phage M13. Fab fragments were fused to the carboxyl-terminal domain of the gene III protein. Phage displaying Fab fragments on their surface, or Phabs, were enriched by 10...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Barbas, C F, Kang, A S, Lerner, R A, Benkovic, S J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52428/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1896445/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.18.7978
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