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Do DNA sequence variants in ABCA1 contribute to HDL cholesterol levels in the general population?
HDL has a key role in reverse cholesterol transport, mobilizing cholesterol from the peripheral tissues to liver. In this process, the ABC transporter A1 (ABCA1) protein controls the efflux of intracellular cholesterol to apoAI, the major apolipoprotein of HDL. Since ABCA1 mutations were discovered...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524241/ https://ncbi.nlm.nih.gov/pubmed/15520856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200423466 |
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