Antitumor activity of miR-34a in peritoneal mesothelioma relies on c-MET and AXL inhibition: persistent activation of ERK and AKT signaling as a possible cytoprotective mechanism

BACKGROUND: The value of microRNAs (miRNAs) as novel targets for cancer therapy is now widely recognized. However, no information is currently available on the expression/functional role of miRNAs in diffuse malignant peritoneal mesothelioma (DMPM), a rapidly lethal disease, poorly responsive to con...

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Bibliographische Detailangaben
Veröffentlicht in:J Hematol Oncol
Hauptverfasser: El Bezawy, Rihan, De Cesare, Michelandrea, Pennati, Marzia, Deraco, Marcello, Gandellini, Paolo, Zuco, Valentina, Zaffaroni, Nadia
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242015/
https://ncbi.nlm.nih.gov/pubmed/28100259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0387-6
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