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Structural basis for the recognition and degradation of host TRIM proteins by Salmonella effector SopA

The hallmark of Salmonella Typhimurium infection is an acute intestinal inflammatory response, which is mediated through the action of secreted bacterial effector proteins. The pro-inflammatory Salmonella effector SopA is a HECT-like E3 ligase, which was previously proposed to activate host RING lig...

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Foilsithe in:Nat Commun
Main Authors: Fiskin, Evgenij, Bhogaraju, Sagar, Herhaus, Lina, Kalayil, Sissy, Hahn, Marcel, Dikic, Ivan
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241803/
https://ncbi.nlm.nih.gov/pubmed/28084320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14004
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