Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis

For decades, identifying the regions of a bacterial chromosome that are necessary for viability has relied on mapping integration sites in libraries of random transposon mutants to find loci that are unable to sustain insertion. To date, these studies have analyzed subsaturated libraries, necessitat...

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Publicat a:mBio
Autors principals: DeJesus, Michael A., Gerrick, Elias R., Xu, Weizhen, Park, Sae Woong, Long, Jarukit E., Boutte, Cara C., Rubin, Eric J., Schnappinger, Dirk, Ehrt, Sabine, Fortune, Sarah M., Sassetti, Christopher M., Ioerger, Thomas R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241402/
https://ncbi.nlm.nih.gov/pubmed/28096490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02133-16
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