Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis

For decades, identifying the regions of a bacterial chromosome that are necessary for viability has relied on mapping integration sites in libraries of random transposon mutants to find loci that are unable to sustain insertion. To date, these studies have analyzed subsaturated libraries, necessitat...

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Veröffentlicht in:mBio
Hauptverfasser: DeJesus, Michael A., Gerrick, Elias R., Xu, Weizhen, Park, Sae Woong, Long, Jarukit E., Boutte, Cara C., Rubin, Eric J., Schnappinger, Dirk, Ehrt, Sabine, Fortune, Sarah M., Sassetti, Christopher M., Ioerger, Thomas R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241402/
https://ncbi.nlm.nih.gov/pubmed/28096490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02133-16
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