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Monomerization of RepA dimers by heat shock proteins activates binding to DNA replication origin.

DnaK is a major heat shock protein of Escherichia coli and the homolog of hsp70 in eukaryotes. We demonstrate the mechanism by which DnaK and another heat shock protein, DnaJ, render the plasmid P1 initiator RepA 100-fold more active for binding to the P1 origin of replication. Activation is the con...

詳細記述

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書誌詳細
主要な著者: Wickner, S, Hoskins, J, McKenney, K
フォーマット: Artigo
言語:Inglês
出版事項: 1991
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC52413/
https://ncbi.nlm.nih.gov/pubmed/1896443
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