Individualized Molecular Analyses Guide Efforts (IMAGE): A Prospective Study of Molecular Profiling of Tissue and Blood in Metastatic Triple Negative Breast Cancer

PURPOSE: The clinical utility of next generation sequencing (NGS) in breast cancer has not been demonstrated. We hypothesized we could perform NGS of a new biopsy from patients with metastatic triple negative breast cancer (TNBC) in a clinically actionable timeframe. EXPERIMENTAL DESIGN: We planned...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Parsons, Heather A., Beaver, Julia A., Cimino-Mathews, Ashley, Ali, Siraj M., Axilbund, Jennifer, Chu, David, Connolly, Roisin M., Cochran, Rory L., Croessmann, Sarah, Clark, Travis, Gocke, Christopher, Jeter, Stacie, Kennedy, Mark, Lauring, Josh, Lee, Justin, Lipson, Doron, Miller, Vincent A., Otto, Geoff A., Rosner, Gary L., Ross, Jeffrey S., Slater, Shannon, Stephens, Phil J., VanDenBerg, Dustin A., Wolff, Antonio C., Young, Lauren E., Zabransky, Daniel J., Zhang, Zhe, Zorzi, Jane, Stearns, Vered, Park, Ben H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241251/
https://ncbi.nlm.nih.gov/pubmed/27489289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1543
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