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Electro-magnetic nano-particle bound Beclin1 siRNA crosses the blood-brain barrier to attenuate the inflammatory effects of HIV-1 infection in vitro
The purpose of this study was to evaluate a novel drug delivery system comprised of ferric-cobalt electro-magnetic nano-material (CoFe(2)O(4)@ BaTiO(3); MENP) bound to siRNA targeting Beclin1 (MENP-siBeclin1) to cross the blood-brain barrier (BBB) and attenuate the neurotoxic effects of HIV-1 infect...
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| Udgivet i: | J Neuroimmune Pharmacol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5241243/ https://ncbi.nlm.nih.gov/pubmed/27287620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-016-9688-3 |
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