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Electro-magnetic nano-particle bound Beclin1 siRNA crosses the blood-brain barrier to attenuate the inflammatory effects of HIV-1 infection in vitro

The purpose of this study was to evaluate a novel drug delivery system comprised of ferric-cobalt electro-magnetic nano-material (CoFe(2)O(4)@ BaTiO(3); MENP) bound to siRNA targeting Beclin1 (MENP-siBeclin1) to cross the blood-brain barrier (BBB) and attenuate the neurotoxic effects of HIV-1 infect...

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Bibliografske podrobnosti
izdano v:J Neuroimmune Pharmacol
Main Authors: Rodriguez, Myosotys, Kaushik, Ajeet, Lapierre, Jessica, Dever, Seth M., El-Hage, Nazira, Nair, Madhavan
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241243/
https://ncbi.nlm.nih.gov/pubmed/27287620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-016-9688-3
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