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Spectroscopic Studies of the EutT Adenosyltransferase from Salmonella enterica: Evidence for a Tetrahedrally Coordinated Divalent Transition Metal Cofactor with Cysteine Ligation

The EutT enzyme from Salmonella enterica, a member of the family of ATP:cobalt(I) corrinoid adenosyltransferase (ACAT) enzymes, requires a divalent transition metal ion for catalysis, with Fe(II) yielding the highest activity. EutT contains a unique cysteine-rich HX(11)CCX(2)C(83) motif (where H and...

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Foilsithe in:Biochemistry
Main Authors: Pallares, Ivan G., Moore, Theodore C., Escalante-Semerena, Jorge C., Brunold, Thomas C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241240/
https://ncbi.nlm.nih.gov/pubmed/28045498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00750
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