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Evaluation of substituted ebselen derivatives as potential trypanocidal agents

Human African trypanosomiasis is a disease of sub-Saharan Africa, where millions are at risk for the illness. The disease, commonly referred to as African sleeping sickness, is caused by an infection by the eukaryotic pathogen, Trypanosoma brucei. Previously, a target-based high throughput screen re...

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Detalles Bibliográficos
Publicado en:Bioorg Med Chem Lett
Main Authors: Gordhan, Heeren M., Patrick, Stephen L., Swasy, Maria I., Hackler, Amber L., Anayee, Mark, Golden, Jennifer E., Morris, James C., Whitehead, Daniel C.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241237/
https://ncbi.nlm.nih.gov/pubmed/28043795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.12.021
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