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Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors
Kinase inhibitors are effective cancer therapies, but tumors frequently develop resistance. Current strategies to circumvent resistance target the same or parallel pathways. We report here that targeting a completely different process, autophagy, can overcome multiple BRAF inhibitor resistance mecha...
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| Izdano u: | eLife |
|---|---|
| Glavni autori: | , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
eLife Sciences Publications, Ltd
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5241115/ https://ncbi.nlm.nih.gov/pubmed/28094001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19671 |
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