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Transient detection of E1-containing adenovirus in saliva after the delivery of a first-generation adenoviral vector to human parotid gland()

BACKGROUND: Radiation-induced salivary hypofunction is a common side-effect of treatment for head and neck cancers. Patients suffer significant morbidity and there is no suitable conventional therapy. We are conducting a Phase I clinical trial, using a first-generation serotype 5 adenoviral (Ad5) ve...

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Bibliografiska uppgifter
I publikationen:J Gene Med
Huvudupphovsmän: Zheng, Changyu, Nikolov, Nikolay P., Alevizos, Ilias, Cotrim, Ana P., Liu, Shuying, McCullagh, Linda, Chiorini, John A., Illei, Gabor G., Baum, Bruce J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241068/
https://ncbi.nlm.nih.gov/pubmed/19941317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.1416
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