Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction

No conventional therapy exists for salivary hypofunction in surviving head and neck cancer patients with Radiation Therapy Oncology Group late grade 2–3 toxicity. We conducted a phase I clinical trial to test the safety and biologic efficacy of serotype 5, adenoviral-mediated aquaporin-1 cDNA transf...

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Bibliografski detalji
Glavni autori: Baum, Bruce J., Alevizos, Ilias, Zheng, Changyu, Cotrim, Ana P., Liu, Shuying, McCullagh, Linda, Goldsmith, Corinne M., Burbelo, Peter D., Citrin, Deborah E., Mitchell, James B., Nottingham, Liesl K., Rudy, Susan F., Van Waes, Carter, Whatley, Millie A., Brahim, Jaime S., Chiorini, John A., Danielides, Stamatina, Turner, R. James, Patronas, Nicholas J., Chen, Clara C., Nikolov, Nikolay P., Illei, Gabor G.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511089/
https://ncbi.nlm.nih.gov/pubmed/23129637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210662109
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