Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction

No conventional therapy exists for salivary hypofunction in surviving head and neck cancer patients with Radiation Therapy Oncology Group late grade 2–3 toxicity. We conducted a phase I clinical trial to test the safety and biologic efficacy of serotype 5, adenoviral-mediated aquaporin-1 cDNA transf...

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Detalhes bibliográficos
Main Authors: Baum, Bruce J., Alevizos, Ilias, Zheng, Changyu, Cotrim, Ana P., Liu, Shuying, McCullagh, Linda, Goldsmith, Corinne M., Burbelo, Peter D., Citrin, Deborah E., Mitchell, James B., Nottingham, Liesl K., Rudy, Susan F., Van Waes, Carter, Whatley, Millie A., Brahim, Jaime S., Chiorini, John A., Danielides, Stamatina, Turner, R. James, Patronas, Nicholas J., Chen, Clara C., Nikolov, Nikolay P., Illei, Gabor G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511089/
https://ncbi.nlm.nih.gov/pubmed/23129637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210662109
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