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Orosomucoid Proteins Interact with the Small Subunit of Serine Palmitoyltransferase and Contribute to Sphingolipid Homeostasis and Stress Responses in Arabidopsis

Serine palmitoyltransferase (SPT), a pyridoxyl-5′-phosphate-dependent enzyme, catalyzes the first and rate-limiting step in sphingolipid biosynthesis. In humans and yeast, orosomucoid proteins (ORMs) negatively regulate SPT and thus play an important role in maintaining sphingolipid levels. Despite...

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Detalhes bibliográficos
Publicado no:Plant Cell
Main Authors: Li, Jian, Yin, Jian, Rong, Chan, Li, Kai-En, Wu, Jian-Xin, Huang, Li-Qun, Zeng, Hong-Yun, Sahu, Sunil Kumar, Yao, Nan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Plant Biologists 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240739/
https://ncbi.nlm.nih.gov/pubmed/27923879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1105/tpc.16.00574
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