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Prion protein gene (PRNP) variants and evidence for strong purifying selection in functionally important regions of bovine exon 3
Amino acid replacements encoded by the prion protein gene (PRNP) have been associated with transmissible and hereditary spongiform encephalopathies in mammalian species. However, an association between bovine spongiform encephalopathy (BSE) and bovine PRNP exon 3 has not been detected. Moreover, lit...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524052/ https://ncbi.nlm.nih.gov/pubmed/15477588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406403101 |
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