Genetic Deletion of the Nociceptin/Orphanin FQ Receptor in the Rat Confers Resilience to the Development of Drug Addiction

The nociceptin (NOP) receptor is a G-protein-coupled receptor whose natural ligand is the NOP/orphanin FQ (N/OFQ) peptide. Evidence from pharmacological studies suggests that the N/OFQ system is implicated in the regulation of several addiction-related phenomena, such as drug intake, withdrawal, and...

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Bibliografiska uppgifter
I publikationen:Neuropsychopharmacology
Huvudupphovsmän: Kallupi, Marsida, Scuppa, Giulia, de Guglielmo, Giordano, Calò, Girolamo, Weiss, Friedbert, Statnick, Michael A, Rorick-Kehn, Linda M, Ciccocioppo, Roberto
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240182/
https://ncbi.nlm.nih.gov/pubmed/27562376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2016.171
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