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Bottom-up proteomics analysis of the secretome of murine islets of Langerhans in elevated glucose levels

Glucotoxicity is a causative agent of type-2 diabetes, where high glucose levels damage the islets of Langerhans resulting in oxidative damage and endoplasmic reticulum stress. We evaluated the secretomes of healthy CD-1 murine islets. Three experimental conditions were investigated in biological tr...

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Detalhes bibliográficos
Publicado no:Analyst
Main Authors: Schmudlach, Andrew, Felton, Jeremy, Kennedy, Robert T., Dovichi, Norman J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239740/
https://ncbi.nlm.nih.gov/pubmed/27966681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6an02268e
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