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Sample preparation protocol for bottom-up proteomic analysis of the secretome of the islets of Langerhans

We evaluate a set of protocols for preparation of the secretome from murine Islets of Langerhans for bottom-up proteomic analysis. Of the protocols evaluated, a filter-aided sample preparation based approach using sodium dodecyl sulfate as a detergent to solubilize proteins generated the most protei...

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Detalhes bibliográficos
Publicado no:Analyst
Main Authors: Schmudlach, Andrew, Felton, Jeremy, Cipolla, Cynthia, Sun, Liangliang, Kennedy, Robert T., Dovichi, Norman J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764456/
https://ncbi.nlm.nih.gov/pubmed/26863548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5an02265g
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