DCC confers susceptibility to depression-like behaviors in humans and mice and is regulated by miR-218

BACKGROUD: Variations in the expression of the Netrin-1 guidance cue receptor DCC (Deleted in colorectal cancer) appear to confer resilience or susceptibility to psychopathologies involving prefrontal cortex (PFC) dysfunction. METHODS: Using postmortem brain tissue, mouse models of defeat stress, an...

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Foilsithe in:Biol Psychiatry
Main Authors: Torres-Berrío, Angélica, Lopez, Juan Pablo, Bagot, Rosemary C., Nouel, Dominique, Dal-Bo, Gregory, Cuesta, Santiago, Zhu, Lei, Manitt, Colleen, Eng, Conrad, Cooper, Helen, Storch, Florian, Turecki, Gustavo, Nestler, Eric J., Flores, Cecilia
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239724/
https://ncbi.nlm.nih.gov/pubmed/27773352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2016.08.017
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