DCC receptors drive prefrontal cortex maturation by determining dopamine axon targeting in adolescence

BACKGROUND: Dopaminergic input to the prefrontal cortex (PFC) increases throughout adolescence and, by establishing precisely localized synapses, calibrates cognitive function. However, why and how mesocortical dopamine axon density increases across adolescence remains completely unknown. METHODS: W...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biol Psychiatry
Prif Awduron: Reynolds, Lauren M., Pokinko, Matthew, Torres Berrío, Angélica, Cuesta, Santiago, Lambert, Laura C., Del Cid Pellitero, Esther, Wodzinski, Michael, Manitt, Colleen, Krimpenfort, Paul, Kolb, Bryan, Flores, Cecilia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723533/
https://ncbi.nlm.nih.gov/pubmed/28720317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2017.06.009
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