DCC receptors drive prefrontal cortex maturation by determining dopamine axon targeting in adolescence

BACKGROUND: Dopaminergic input to the prefrontal cortex (PFC) increases throughout adolescence and, by establishing precisely localized synapses, calibrates cognitive function. However, why and how mesocortical dopamine axon density increases across adolescence remains completely unknown. METHODS: W...

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Publicat a:Biol Psychiatry
Autors principals: Reynolds, Lauren M., Pokinko, Matthew, Torres Berrío, Angélica, Cuesta, Santiago, Lambert, Laura C., Del Cid Pellitero, Esther, Wodzinski, Michael, Manitt, Colleen, Krimpenfort, Paul, Kolb, Bryan, Flores, Cecilia
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723533/
https://ncbi.nlm.nih.gov/pubmed/28720317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2017.06.009
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