Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function

Brown (BAT) and white (WAT) adipose tissues play distinct roles in maintaining whole-body energy homeostasis, and their dysfunction can contribute to non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes. The AMP-activated protein kinase (AMPK) is a cellular energy sensor, but its role in re...

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Veröffentlicht in:Cell Metab
Hauptverfasser: Mottillo, Emilio P., Desjardins, Eric M., Crane, Justin D., Smith, Brennan K., Green, Alex E., Ducommun, Serge, Henriksen, Tora I., Rebalka, Irena A., Razi, Aida, Sakamoto, Kei, Scheele, Camilla, Kemp, Bruce E., Hawke, Thomas J., Ortega, Joaquin, Granneman, James G., Steinberg, Gregory R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239668/
https://ncbi.nlm.nih.gov/pubmed/27411013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.06.006
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