TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype

Tumor-associated macrophages (TAMs) are a major component of leukocytic infiltrate in tumors, which facilitates tumor progression and promotes inflammation. TGF-β promotes the differentiation of non-activated macrophages into a TAM-like (M2-like) phenotype; however, the underlying mechanisms are not...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Zhang, Fan, Wang, Hongsheng, Wang, Xianfeng, Jiang, Guanmin, Liu, Hao, Zhang, Ge, Wang, Hao, Fang, Rui, Bu, Xianzhang, Cai, Shaohui, Du, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239552/
https://ncbi.nlm.nih.gov/pubmed/27418133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10561
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