A key role for transketolase-like 1 in tumor metabolic reprogramming

Metabolic reprogramming, a crucial cancer hallmark, shifts metabolic pathways such as glycolysis, tricarboxylic acid cycle or lipogenesis, to enable the growth characteristics of cancer cells. Here, we provide evidence that transketolase-like 1 (TKTL1) orchestrates aerobic glycolysis, fatty acid and...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Diaz-Moralli, Santiago, Aguilar, Esther, Marin, Silvia, Coy, Johannes F., Dewerchin, Mieke, Antoniewicz, Maciek R., Meca-Cortés, Oscar, Notebaert, Leen, Ghesquière, Bart, Eelen, Guy, Thomson, Timothy M., Carmeliet, Peter, Cascante, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239521/
https://ncbi.nlm.nih.gov/pubmed/27391434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10429
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