Immunotherapy of acute leukemia by chimeric antigen receptor-modified lymphocytes using an improved Sleeping Beauty transposon platform

Chimeric antigen receptor (CAR)-modified T-cell adoptive immunotherapy is a remarkable therapeutic option proven effective in the treatment of hematological malignancies. In order to optimize cell manufacturing, we sought to develop a novel clinical-grade protocol to obtain CAR-modified cytokine-ind...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Magnani, Chiara F., Turazzi, Nice, Benedicenti, Fabrizio, Calabria, Andrea, Tenderini, Erika, Tettamanti, Sarah, Attianese, Greta M.P. Giordano, Cooper, Laurence J.N., Aiuti, Alessandro, Montini, Eugenio, Biondi, Andrea, Biagi, Ettore
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239498/
https://ncbi.nlm.nih.gov/pubmed/27323395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9955
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