The coexistence of MET over-expression and an EGFR T790M mutation is related to acquired resistance to EGFR tyrosine kinase inhibitors in advanced non-small cell lung cancer

MET overexpression and the EGFR T790M mutation are both associated with acquired resistance (AR) to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) in advanced non-small cell lung cancer (NSCLC). We characterized the frequency, underlying molecular mechanisms, and subsequent...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Gou, Lan-Ying, Li, An-Na, Yang, Jin-Ji, Zhang, Xu-Chao, Su, Jian, Yan, Hong-Hong, Xie, Zhi, Lou, Na-Na, Liu, Si-Yang, Dong, Zhong-Yi, Gao, Hong-Fei, Zhou, Qing, Zhong, Wen-Zhao, Xu, Chong-Rui, Wu, Yi-Long
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239477/
https://ncbi.nlm.nih.gov/pubmed/27259997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9697
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