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An essential pathway links FLT3-ITD, HCK and CDK6 in acute myeloid leukemia
CDK4/CDK6 and RB proteins drive the progression through the G1 phase of the cell cycle. In acute myeloid leukemia (AML), the activity of the CDK/Cyclin D complex is increased. The mechanism involved is unknown, as are the respective roles played by CDK4 or CDK6 in this process. Here, we report that...
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| Publicado no: | Oncotarget |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5239466/ https://ncbi.nlm.nih.gov/pubmed/27323399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9965 |
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