The piggyBac transposon-derived genes TPB1 and TPB6 mediate essential transposon-like excision during the developmental rearrangement of key genes in Tetrahymena thermophila

Ciliated protozoans perform extreme forms of programmed somatic DNA rearrangement during development. The model ciliate Tetrahymena thermophila removes 34% of its germline micronuclear genome from somatic macronuclei by excising thousands of internal eliminated sequences (IESs), a process that share...

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Библиографические подробности
Опубликовано в: :Genes Dev
Главные авторы: Cheng, Chao-Yin, Young, Janet M., Lin, Chih-Yi Gabriela, Chao, Ju-Lan, Malik, Harmit S., Yao, Meng-Chao
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238731/
https://ncbi.nlm.nih.gov/pubmed/28087716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.290460.116
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