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CTCF-mediated topological boundaries during development foster appropriate gene regulation

The genome is organized into repeating topologically associated domains (TADs), each of which is spatially isolated from its neighbor by poorly understood boundary elements thought to be conserved across cell types. Here, we show that deletion of CTCF (CCCTC-binding factor)-binding sites at TAD and...

詳細記述

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書誌詳細
出版年:Genes Dev
主要な著者: Narendra, Varun, Bulajić, Milica, Dekker, Job, Mazzoni, Esteban O., Reinberg, Danny
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238725/
https://ncbi.nlm.nih.gov/pubmed/28087711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.288324.116
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