CTCF regulates the human p53 gene through direct interaction with its natural antisense transcript, Wrap53

The multifunctional CCCTC-binding factor (CTCF) protein exhibits a broad range of functions, including that of insulator and higher-order chromatin organizer. We found that CTCF comprises a previously unrecognized region that is necessary and sufficient to bind RNA (RNA-binding region [RBR]) and is...

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Detalhes bibliográficos
Main Authors: Saldaña-Meyer, Ricardo, González-Buendía, Edgar, Guerrero, Georgina, Narendra, Varun, Bonasio, Roberto, Recillas-Targa, Félix, Reinberg, Danny
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015496/
https://ncbi.nlm.nih.gov/pubmed/24696455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.236869.113
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