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Targeting Argonaute to chromatin
In many eukaryotes, siRNAs bound to Argonaute proteins guide chromatin-modifying enzymes to complementary loci, resulting in transcriptional gene silencing. Multiple lines of evidence indicate that siRNAs base-pair with longer RNAs produced at target loci, but the possibility that siRNAs base-pair d...
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| Publicado no: | Genes Dev |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5238723/ https://ncbi.nlm.nih.gov/pubmed/28087710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.294900.116 |
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