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Targeting Argonaute to chromatin

In many eukaryotes, siRNAs bound to Argonaute proteins guide chromatin-modifying enzymes to complementary loci, resulting in transcriptional gene silencing. Multiple lines of evidence indicate that siRNAs base-pair with longer RNAs produced at target loci, but the possibility that siRNAs base-pair d...

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Foilsithe in:Genes Dev
Main Authors: Wendte, Jered M., Pikaard, Craig S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238723/
https://ncbi.nlm.nih.gov/pubmed/28087710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.294900.116
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